LatinoReview.com's No. 6 featurette on the right side of the page about "Cars" should be of considerable interest to Route 66 aficionados.
It's titled "Kickin' It on Route 66." It contains footage of author Michael Wallis taking the Pixar crew down the Mother Road during their research for the film. Roadies should be able to recognize a lot of sights in the footage, especially in Oklahoma and Texas.